Odd Man Out

a.k.a. Wednesday's brain bender...

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Which of the words below is least like the others and why? (The difference has nothing to do with vowels, consonants or syllables.)

• TWIN
• CHIME
• SCORE
• PLATE
• CARE
• HAT

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Answer to be found later in the comments! :)

Update: Today's smartypants is bigdocmcd! Yay! And according to the comments -- impressive...